Alair® Bronchial Thermoplasty System by Asthmatx

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By radically changing the standard of care, Asthmatx will become the leading provider of therapeutic medical devices for patients who suffer from asthma.

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What is the AIR2 Trial?
The AIR2 Trial: The objective of this randomized, double blind, sham-controlled study is to evaluate the safety and efficacy of Bronchial Thermoplasty with the Alair® System in a population of subjects with severe asthma who are still symptomatic despite being managed on conventional therapy.

Mayse M, Laviolette M, Rubin A, et al, Clinical Pearls for Bronchial Thermoplasty, J of Bronchol 2007;14:115-123

Clinical Pearls for Bronchial Thermoplasty

How I Do It

Mayse, Martin L. MD; Laviolette, Michel MD; Rubin, Adalberto S. MD; Lampron, Noel MD; Simoff, Michael MD; Duhamel, David MD; Musani, Ali I. MD; Yung, Rex C. MD; Mehta, Atul C. MD

Abstract

The development of bronchial thermoplasty, an investigational outpatient bronchoscopic procedure for asthma, has captured the interest of the interventional pulmonologist. Promising early clinical studies have demonstrated that bronchial thermoplasty may result in an improvement in asthma control. Bronchial thermoplasty involves the controlled delivery of radiofrequency electrical energy to the airway wall via a special catheter electrode array. Bronchial thermoplasty is performed under conscious sedation and typically results in a bronchoscopy that is longer in duration than most currently performed bronchoscopic procedures. Effective patient management is, therefore, critically important to maximize patient comfort and safety. We describe our technique for bronchial thermoplasty, highlighting the importance of bronchoscopy experience, careful patient selection, patient preparation, patient management, and postoperative follow-up.